Biological Safety

Providing support, in the form of risk assessment, review, consultation and training, for research at UC Berkeley that involves the use of recombinant DNA, biohazardous materials and biological toxins.

Lentivirus Exposure Control Plan with Assessment Questionnaire - UHS

2024

Complete this attachment and upload it into your BUA if your research includes:

Lentiviral vector use by labs with access to University Health Services.

Recombinant Nucleic Acid Template(s)

2024

Complete this attachment and upload it into your BUA if your research includes:

Recombinant nucleic acid experiments involving cells, plants, animals, microorganisms, and viruses.

Transgenic organisms, viruses, or cells grown, used, or stored on campus.

Controlled Substances

Controlled Substances

UC Berkeley’s Controlled Substances (CS) program outlines required procedures pertaining to the procurement, use, storage, inventory, and disposal of controlled substances to comply with Federal Drug Enforcement Administration (DEA) regulations. These procedures apply to all research and teaching activities using controlled substances.

Contact the EH&S Controlled Substances Program...

Attestation, Vivarium Safety Awareness

Office of Environment, Health & Safety
2023
In accordance with UC Berkeley’s Animal Care and Use Committee (ACUC) and the Office of Laboratory Animal Care (OLAC)’s guidelines and procedures, it is the responsibility of ALL University workers and contractors to ensure the health and well-being of animals used in research and teaching. This attestation form confirms animal facility workers and contractors have reviewed the information...

Vivarium Safety, Fact Sheet

Office of Environment, Health & Safety
2023

Guidance for Animal Facility Workers & Contractors

In accordance with UC Berkeley’s Animal Care and Use Committee (ACUC) and the Office of Laboratory Animal Care (OLAC)’s guidelines and procedures, it is the responsibility of ALL University workers and contractors to ensure the health and well-being of animals used in research and...

What considerations do I need to make when shipping a biological substance?

Biological and Infectious Substances regulated for transportation include those identified as Infectious Substances-Category A, Biological Substances-Category B, Genetically modified organisms or micro-organisms. Exempt Human specimen and Exempt Animal specimen, although exempt per the regulations, require minimum packaging and markings when transported by air.

Infectious Substance (Division 6.2)

A material known or reasonably expected to contain a pathogen. A pathogen is a micro- organism (including bacteria, viruses, rickettsiae, parasites, fungi) or other agent,...

Committee for Laboratory and Environmental Biosafety (CLEB)

The Committee for Laboratory and Environmental Biosafety (CLEB) serves as UC Berkeley’s Institutional Biosafety Committee (IBC). CLEB is comprised of subject matter experts, an animal health expert, an occupational physician, as well as community members.

The committee meets to review Biological Use Authorizations on the first Monday of every month 2:00 pm - 4:00 pm via Zoom. RSVP by email is required. If you wish to attend a committee meeting or have any other questions regarding CLEB, please contact...

Biological Use Authorization Application

Office of Environment, Health & Safety
2022
Biological Use Authorization (BUA) Application Form

Principal Investigators (PIs) will need to submit a Biological Use Authorization (BUA) if working with biological agents including:

recombinant DNA synthetic nucleic acids WHO Risk Group 2 or higher pathogens biological toxins material of human or non-human primate origin, including cell lines

To determine if the agent you plan to work with is considered Risk Group 2 or higher, please reference the...

Dual Use Research of Concern

Dual Use Research of Concern (DURC) is life sciences research that, based on current understanding, can be reasonably anticipated to provide knowledge, information, products, or technologies that could be directly misapplied to pose a significant threat with broad potential consequences to public health and safety, agricultural crops and other plants, animals, the environment, materiel, or national security.


The U.S. government has developed a policy establishing regular review of government-funded or -conducted research with 15 high-consequence pathogens and...

Biological Safety

Providing support, in the form of risk assessment, review, consultation and training, for research at UC Berkeley that involves the use of recombinant DNA, biohazardous materials and biological toxins.

Biosafety How Do I: collapse all...